Melatonin reverses H(2)O(2)-induced premature senescence in mesenchymal stem cells via the SIRT1-dependent pathway

Mesenchymal stem cells (MSCs) represent an attractive source for stem cell-based regenerative therapy, but they are vulnerable to oxidative stress-induced premature senescence in pathological conditions. We previously reported antioxidant and antiarthritic effects of melatonin on MSCs against proinf...

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Detalhes bibliográficos
Publicado no:J Pineal Res
Main Authors: Zhou, Long, Chen, Xi, Liu, Tao, Gong, Yihong, Chen, Sijin, Pan, Guoqing, Cui, Wenguo, Luo, Zong-Ping, Pei, Ming, Yang, Huilin, He, Fan
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4523475/
https://ncbi.nlm.nih.gov/pubmed/25975679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jpi.12250
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