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Resveratrol Induced Premature Senescence Is Associated with DNA Damage Mediated SIRT1 and SIRT2 Down-Regulation

The natural polyphenolic compound resveratrol (3,4,5-trihydroxy-trans-stilbene) has broad spectrum health beneficial activities including antioxidant, anti-inflammatory, anti-aging, anti-cancer, cardioprotective, and neuroprotective effects. Remarkably, resveratrol also induces apoptosis and cellula...

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Foilsithe in:PLoS One
Main Authors: Kilic Eren, Mehtap, Kilincli, Ayten, Eren, Özkan
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4414559/
https://ncbi.nlm.nih.gov/pubmed/25924011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0124837
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