SIRT6 promotes osteogenic differentiation of mesenchymal stem cells through BMP signaling

SIRT6 has been identified as an H3K9 deacetylase and a critical regulator of genome stability, telomere integrity, and metabolic homeostasis. Sirt6-deficient mice displayed dramatic phenotypes including profound lymphopenia, loss of subcutaneous fat, lordokyphosis and low bone marrow density. Here,...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Zhang, Ping, Liu, Yunsong, Wang, Yuejun, Zhang, Min, Lv, Longwei, Zhang, Xiao, Zhou, Yongsheng
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5578964/
https://ncbi.nlm.nih.gov/pubmed/28860594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-10323-z
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller