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RSPO3-LGR4 Regulates Osteogenic Differentiation Of Human Adipose-Derived Stem Cells Via ERK/FGF Signalling

The four R-spondins (RSPOs) and their three related receptors, LGR4, 5 and 6, have emerged as a major ligand-receptor system with critical roles in development and stem cell survival. However, the exact roles of the RSPO-LGR system in osteogenesis remain largely unknown. In the present study, we sho...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zhang, Min, Zhang, Ping, Liu, Yunsong, Lv, Longwei, Zhang, Xiao, Liu, Hao, Zhou, Yongsheng
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5318871/
https://ncbi.nlm.nih.gov/pubmed/28220828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep42841
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