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Identification of an Essential Cytoplasmic Region of Interleukin-7 Receptor α Subunit in B-Cell Development
Interleukin-7 (IL-7) is essential for lymphocyte development. To identify the functional subdomains in the cytoplasmic tail of the IL-7 receptor (IL-7R) α chain, here, we constructed a series of IL-7Rα deletion mutants. We found that IL-7Rα-deficient hematopoietic progenitor cells (HPCs) gave rise t...
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| Опубликовано в: : | Int J Mol Sci |
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| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
MDPI
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6165445/ https://ncbi.nlm.nih.gov/pubmed/30149646 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19092522 |
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