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IL-7 specifies B cell fate at the CLP to pre-proB transition stage by maintaining EBF expression
Interleukin 7 (IL-7) plays a critical role in B cell fate decision by regulating early B cell factor (EBF) expression. However, it was not clear when IL-7 stimulation is necessary in hemato/lymphopoiesis in adult mice. Here we show that pre-proB cells derived from IL-7(−/−) mice have lost B cell pot...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2586338/ https://ncbi.nlm.nih.gov/pubmed/18566404 |
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