Targeting TGFβ Signaling to Address Fibrosis Using Antisense Oligonucleotides

Fibrosis results from the excessive accumulation of extracellular matrix in chronically injured tissue. The fibrotic process is governed by crosstalk between many signaling pathways. The search for an effective treatment is further complicated by the fact that there is a degree of tissue-specificity...

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Publicat a:Biomedicines
Autors principals: March, James T., Golshirazi, Golnoush, Cernisova, Viktorija, Carr, Heidi, Leong, Yee, Lu-Nguyen, Ngoc, Popplewell, Linda J.
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2018
Matèries:
Review
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6164894/
https://ncbi.nlm.nih.gov/pubmed/29941814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines6030074
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