Mechanism of Lakoochin A Inducing Apoptosis of A375.S2 Melanoma Cells through Mitochondrial ROS and MAPKs Pathway

Malignant melanoma is developed from pigment-containing cells, melanocytes, and primarily found on the skin. Malignant melanoma still has a high mortality rate, which may imply a lack of therapeutic agents. Lakoochin A, a compound isolated from Artocarpus lakoocha and Artocarpus xanthocarpus, has an...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Peng, Kuo-Ti, Chiang, Yao-Chang, Ko, Horng-Huey, Chi, Pei-Ling, Tsai, Chia-Lan, Ko, Ming-I, Lee, Ming-Hsueh, Hsu, Lee-Fen, Lee, Chiang-Wen
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2018
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6164788/
https://ncbi.nlm.nih.gov/pubmed/30200660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19092649
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