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Cudraflavone C Induces Apoptosis of A375.S2 Melanoma Cells through Mitochondrial ROS Production and MAPK Activation

Melanoma is the most malignant form of skin cancer and is associated with a very poor prognosis. The aim of this study was to evaluate the apoptotic effects of cudraflavone C on A375.S2 melanoma cells and to determine the underlying mechanisms involved in apoptosis. Cell viability was determined usi...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Lee, Chiang-Wen, Yen, Feng-Lin, Ko, Horng-Huey, Li, Shu-Yu, Chiang, Yao-Chang, Lee, Ming-Hsueh, Tsai, Ming-Horng, Hsu, Lee-Fen
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5535998/
https://ncbi.nlm.nih.gov/pubmed/28703746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18071508
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