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Kinesin-2 Controls the Motility of RAB5 Endosomes and Their Association with the Spindle in Mitosis

RAB5 is a small GTPase that belongs to the wide family of Rab proteins and localizes on early endosomes. In its active GTP-bound form, RAB5 recruits downstream effectors that, in turn, are responsible for distinct aspects of early endosome function, including their movement along microtubules. We pr...

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Détails bibliographiques
Publié dans:Int J Mol Sci
Auteurs principaux: Pupo, Emanuela, Avanzato, Daniele, Scianna, Marco, Oldani, Amanda, Serini, Guido, Lanzetti, Letizia
Format: Artigo
Langue:Inglês
Publié: MDPI 2018
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6163544/
https://ncbi.nlm.nih.gov/pubmed/30200238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19092575
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