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Rab11-endosomes contribute to mitotic spindle orientation

During interphase, Rab11-GTPase-containing endosomes recycle endocytic cargo. However, little is known about Rab11 and endosomes in mitosis. Here we show that Rab11 localizes to the mitotic spindle and regulates dynein-dependent endosome localization at poles. We found that mitotic recycling endosom...

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Bibliografiske detaljer
Main Authors: Hehnly, Heidi, Doxsey, Stephen
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4030695/
https://ncbi.nlm.nih.gov/pubmed/24561039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2014.01.014
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