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KRAS-Driven Metabolic Rewiring Reveals Novel Actionable Targets in Cancer

Tumors driven by mutant KRAS are among the most aggressive and refractory to treatment. Unfortunately, despite the efforts, targeting alterations of this GTPase, either directly or by acting on the downstream signaling cascades, has been, so far, largely unsuccessful. However, recently, novel therap...

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Bibliografiska uppgifter
I publikationen:Front Oncol
Huvudupphovsmän: Pupo, Emanuela, Avanzato, Daniele, Middonti, Emanuele, Bussolino, Federico, Lanzetti, Letizia
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2019
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6730590/
https://ncbi.nlm.nih.gov/pubmed/31544066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.00848
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