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Neutralizing anti-drug antibodies in Fabry disease have no obvious clinical impact?

Fabry disease (FD) is a rare X-linked disorder caused by a deficiency of lysosomal α-galactosidase A activity. Treatment with recombinant enzyme replacement therapy is available since 2001 and the effects of anti-drug antibodies (ADA) on therapy efficacy and disease outcome in affected patients have...

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Bibliografiska uppgifter
I publikationen:Orphanet J Rare Dis
Huvudupphovsmän: Lenders, Malte, Schmitz, Boris, Brand, Stefan-Martin, Brand, Eva
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6162957/
https://ncbi.nlm.nih.gov/pubmed/30268124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13023-018-0916-1
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