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Serum-Mediated Inhibition of Enzyme Replacement Therapy in Fabry Disease

Fabry disease (FD) is a progressive multisystemic disorder, treatable with recombinant enzyme replacement therapy (agalsidase). However, recent studies suggest an endogenous inhibition of agalsidase in patients with FD, as reported for other lysosomal storage diseases. To assess the clinical consequ...

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Detalles Bibliográficos
Publicado en:J Am Soc Nephrol
Autores principales: Lenders, Malte, Stypmann, Jörg, Duning, Thomas, Schmitz, Boris, Brand, Stefan-Martin, Brand, Eva
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Nephrology 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4696578/
https://ncbi.nlm.nih.gov/pubmed/25933799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2014121226
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