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Generation and Characterization of a Polyclonal Human Reference Antibody to Measure Anti-Drug Antibody Titers in Patients with Fabry Disease

Male patients with Fabry disease (FD) are at high risk for the formation of antibodies to recombinant α-galactosidase A (AGAL), used for enzyme replacement therapy. Due to the rapid disease progression, the identification of patients at risk is highly warranted. However, currently suitable reference...

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Foilsithe in:Int J Mol Sci
Main Authors: Lenders, Malte, Scharnetzki, David, Heidari, Ali, Di Iorio, Daniele, Wegner, Seraphine Valeska, Brand, Eva
Formáid: Artigo
Teanga:Inglês
Foilsithe: MDPI 2021
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7961705/
https://ncbi.nlm.nih.gov/pubmed/33800950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22052680
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