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Two-pore channels and disease()

Two-pore channels (TPCs) are Ca(2+)-permeable endo-lysosomal ion channels subject to multi-modal regulation. They mediate their physiological effects through releasing Ca(2+) from acidic organelles in response to cues such as the second messenger, NAADP. Here, we review emerging evidence linking TPC...

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Veröffentlicht in:Biochim Biophys Acta
Hauptverfasser: Patel, Sandip, Kilpatrick, Bethan S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier Pub. Co 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6162333/
https://ncbi.nlm.nih.gov/pubmed/29746898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2018.05.004
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