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A novel malic acid-enhanced method for the analysis of 5-methyl-2′-deoxycytidine, 5-hydroxymethyl-2′-deoxycytidine, 5-methylcytidine and 5-hydroxymethylcytidine in human urine using hydrophilic interaction liquid chromatography-tandem mass spectrometry

5-Methyl-2′-deoxycytidine (5-mdC), 5-hydroxymethyl-2′-deoxycytidine (5-hmdC), 5-methylcytidine (5-mrC) and 5-hydroxymethylcytidine (5-hmrC) are epigenetic marks of DNA and RNA, and aberrant levels of these modified nucleosides were found to be associated with various cancers. Urine is a preferred so...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Anal Chim Acta
Egile Nagusiak: Guo, Cheng, Xie, Cong, Chen, Qin, Cao, Xiaoji, Guo, Mengzhe, Zheng, Shu, Wang, Yinsheng
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6162048/
https://ncbi.nlm.nih.gov/pubmed/30193624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.aca.2018.06.081
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