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Synthesis and Multiple Incorporations of 2′‐O‐Methyl‐5‐hydroxymethylcytidine, 5‐Hydroxymethylcytidine and 5‐Formylcytidine Monomers into RNA Oligonucleotides
The synthesis of 2′‐O‐methyl‐5‐hydroxymethylcytidine (hm(5)Cm), 5‐hydroxymethylcytidine (hm(5)C) and 5‐formylcytidine (f(5)C) phosphoramidite monomers has been developed. Optimisation of mild post‐synthetic deprotection conditions enabled the synthesis of RNA containing all four naturally occurring...
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| Publicado no: | Chembiochem |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5779611/ https://ncbi.nlm.nih.gov/pubmed/28901692 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201700492 |
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