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The novel NADPH oxidase 4 selective inhibitor GLX7013114 counteracts human islet cell death in vitro
It has been proposed that pancreatic beta-cell dysfunction in type 2 diabetes is promoted by oxidative stress caused by NADPH oxidase (Nox) over-activity. The aim of the present study was to evaluate the efficacy of novel Nox inhibitors as protective agents against cytokine- or high glucose + palmit...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6161897/ https://ncbi.nlm.nih.gov/pubmed/30265686 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0204271 |
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