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Improved Vascular Engraftment and Graft Function After Inhibition of the Angiostatic Factor Thrombospondin-1 in Mouse Pancreatic Islets

OBJECTIVE—Insufficient development of a new intra-islet capillary network after transplantation may be one contributing factor to the failure of islet grafts in clinical transplantation. The present study tested the hypothesis that the angiostatic factor thrombospondin-1 (TSP-1), which is normally p...

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Main Authors: Olerud, Johan, Johansson, Magnus, Lawler, Jack, Welsh, Nils, Carlsson, Per-Ola
格式: Artigo
語言:Inglês
出版: American Diabetes Association 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2453615/
https://ncbi.nlm.nih.gov/pubmed/18420490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db07-0724
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