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Adenoviral-induced islet cell cytotoxicity is not counteracted by Bcl-2 overexpression.

BACKGROUND: The ability to transfer immunoregulatory, cytoprotective, or anti-apoptotic genes into pancreatic islet cells may allow enhanced resistance against the autoimmune destruction of these cells in type 1 diabetes. We describe here an inducible transduction system for expression of the anti-a...

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Hlavní autoři: Barbu, Andreea R., Akusjärvi, Goran, Welsh, Nils
Médium: Artigo
Jazyk:Inglês
Vydáno: 2002
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2039949/
https://ncbi.nlm.nih.gov/pubmed/12520090
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