The tyrosine kinase FRK/RAK participates in cytokine-induced islet cell cytotoxicity

Hallmarks of the inflammatory process in Type I diabetes are macrophage activation, local release of β-cell-toxic cytokines and infiltration of cytotoxic T lymphocytes. We have observed recently that mice overexpressing active FRK (fyn-related kinase)/RAK (previously named GTK/Bsk/IYK, where GTK sta...

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Bibliographic Details
Main Authors: Welsh, Michael, Welsh, Charlotte, Ekman, Maria, Dixelius, Johan, HäGERKVIST, Robert, ANNERéN, Cecilia, Åkerblom, Björn, Mahboobi, Siavosh, Chandrasekharan, Subhashini, Liu, Edison T.
Format: Artigo
Language:Inglês
Published: Portland Press Ltd. 2004
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1133939/
https://ncbi.nlm.nih.gov/pubmed/15186217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20040285
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