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GTK tyrosine kinase-induced alteration of IRS-protein signalling in insulin producing cells.

BACKGROUND: Insulin receptor substrate proteins (IRS) mediate various effects of insulin, including regulation of glucose homeostasis, cell growth and survival. To understand the underlying mechanisms explaining the effects of the Src-related tyrosine kinase GTK on beta-cell proliferation and surviv...

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Detalhes bibliográficos
Main Authors: Annerén, Cecilia, Welsh, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2039956/
https://ncbi.nlm.nih.gov/pubmed/12520087
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