N-(2′-Hydroxyphenyl)-2-propylpentanamide (OH-VPA), a histone deacetylase inhibitor, induces the release of nuclear HMGB1 and modifies ROS levels in HeLa cells

N-(2′-Hydroxyphenyl)-2-propylpentanamide (OH-VPA) is a valproic acid (VPA) derivative with improved antiproliferative activity toward breast cancer (MCF-7, MDA-MB-231, and SKBr3) and human cervical cancer cell lines (HeLa) compared to that of VPA. However, the pharmacological mechanism of OH-VPA act...

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Vydáno v:Oncotarget
Hlavní autoři: Contis-Montes de Oca, Arturo, Rodarte-Valle, Estefanía, Rosales-Hernández, Martha Cecilia, Abarca-Rojano, Edgar, Rojas-Hernández, Saúl, Fragoso-Vázquez, Manuel Jonathan, Mendieta-Wejebe, Jessica Elena, Correa-Basurto, Ana María, Vázquez-Moctezuma, Ismael, Correa-Basurto, José
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2018
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6161798/
https://ncbi.nlm.nih.gov/pubmed/30279967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26077
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