N-(2′-Hydroxyphenyl)-2-Propylpentanamide (HO-AAVPA) Inhibits HDAC1 and Increases the Translocation of HMGB1 Levels in Human Cervical Cancer Cells

N-(2′-hydroxyphenyl)-2-propylpentanamide (HO-AAVPA) is a VPA derivative designed to be a histone deacetylase (HDAC) inhibitor. HO-AAVPA has better antiproliferative effect than VPA in cancer cell lines. Therefore, in this work, the inhibitory effect of HO-AAVPA on HDAC1, HDAC6, and HDAC8 was determi...

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Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Sixto-López, Yudibeth, Rosales-Hernández, Martha Cecilia, Contis-Montes de Oca, Arturo, Fragoso-Morales, Leticia Guadalupe, Mendieta-Wejebe, Jessica Elena, Correa-Basurto, Ana María, Abarca-Rojano, Edgar, Correa-Basurto, José
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7461584/
https://ncbi.nlm.nih.gov/pubmed/32824279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21165873
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