Design, Synthesis, In Vitro, and Initial In Vivo Evaluation of Heterobivalent Peptidic Ligands Targeting Both NPY(Y(1))- and GRP-Receptors—An Improvement for Breast Cancer Imaging?

Heterobivalent peptidic ligands (HBPLs), designed to address two different receptors independently, are highly promising tumor imaging agents. For example, breast cancer has been shown to concomitantly and complementarily overexpress the neuropeptide Y receptor subtype 1 (NPY(Y(1))R) as well as the...

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Enregistré dans:
Détails bibliographiques
Publié dans:Pharmaceuticals (Basel)
Auteurs principaux: Vall-Sagarra, Alicia, Litau, Shanna, Decristoforo, Clemens, Wängler, Björn, Schirrmacher, Ralf, Fricker, Gert, Wängler, Carmen
Format: Artigo
Langue:Inglês
Publié: MDPI 2018
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6161111/
https://ncbi.nlm.nih.gov/pubmed/29973529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph11030065
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