Design, Synthesis, In Vitro, and Initial In Vivo Evaluation of Heterobivalent Peptidic Ligands Targeting Both NPY(Y(1))- and GRP-Receptors—An Improvement for Breast Cancer Imaging?

Heterobivalent peptidic ligands (HBPLs), designed to address two different receptors independently, are highly promising tumor imaging agents. For example, breast cancer has been shown to concomitantly and complementarily overexpress the neuropeptide Y receptor subtype 1 (NPY(Y(1))R) as well as the...

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Detalhes bibliográficos
Publicado no:Pharmaceuticals (Basel)
Main Authors: Vall-Sagarra, Alicia, Litau, Shanna, Decristoforo, Clemens, Wängler, Björn, Schirrmacher, Ralf, Fricker, Gert, Wängler, Carmen
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6161111/
https://ncbi.nlm.nih.gov/pubmed/29973529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph11030065
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