Inhibition of Notch1 induces population and suppressive activity of regulatory T cell in inflammatory arthritis

Inhibition of Notch signalling has shown anti-inflammatory properties in vivo and in vitro models of rheumatoid arthritis (RA). The objective of this study was to determine whether Notch1 might play a role in regulating T-regulatory cells (Tregs) in animal models of RA. Methods: Collagen-induced art...

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Publicat a:Theranostics
Autors principals: Choi, Bo Youn, Choi, Yuri, Park, Jong-Sung, Kang, Li-Jung, Baek, Seung Hyun, Park, Jin Su, Bahn, Gahee, Cho, Yoonsuk, Kim, Hark Kyun, Han, Jihoon, Sul, Jae Hoon, Baik, Sang-Ha, Hyun, Dong Hoon, Arumugam, Thiruma V., Yang, Siyoung, Han, Jeung-Whan, Kang, Young Mo, Cho, Yong-Woo, Park, Jae Hyung, Jo, Dong-Gyu
Format: Artigo
Idioma:Inglês
Publicat: Ivyspring International Publisher 2018
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6160763/
https://ncbi.nlm.nih.gov/pubmed/30279738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.26093
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