Inhibition of Drp1 Ameliorates Synaptic Depression, Aβ Deposition, and Cognitive Impairment in an Alzheimer's Disease Model

Excessive mitochondrial fission is a prominent early event and contributes to mitochondrial dysfunction, synaptic failure, and neuronal cell death in the progression of Alzheimer's disease (AD). However, it remains to be determined whether inhibition of excessive mitochondrial fission is benefi...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Baek, Seung Hyun, Park, So Jung, Jeong, Jae In, Kim, Sung Hyun, Han, Jihoon, Kyung, Jae Won, Baik, Sang-Ha, Choi, Yuri, Choi, Bo Youn, Park, Jin Su, Bahn, Gahee, Shin, Ji Hyun, Jo, Doo Sin, Lee, Joo-Yong, Jang, Choon-Gon, Arumugam, Thiruma V., Kim, Jongpil, Han, Jeung-Whan, Koh, Jae-Young, Cho, Dong-Hyung, Jo, Dong-Gyu
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2017
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6596467/
https://ncbi.nlm.nih.gov/pubmed/28432138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2385-16.2017
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