Inhibition of Drp1 Ameliorates Synaptic Depression, Aβ Deposition, and Cognitive Impairment in an Alzheimer's Disease Model

Excessive mitochondrial fission is a prominent early event and contributes to mitochondrial dysfunction, synaptic failure, and neuronal cell death in the progression of Alzheimer's disease (AD). However, it remains to be determined whether inhibition of excessive mitochondrial fission is benefi...

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Bibliografiset tiedot
Julkaisussa:J Neurosci
Päätekijät: Baek, Seung Hyun, Park, So Jung, Jeong, Jae In, Kim, Sung Hyun, Han, Jihoon, Kyung, Jae Won, Baik, Sang-Ha, Choi, Yuri, Choi, Bo Youn, Park, Jin Su, Bahn, Gahee, Shin, Ji Hyun, Jo, Doo Sin, Lee, Joo-Yong, Jang, Choon-Gon, Arumugam, Thiruma V., Kim, Jongpil, Han, Jeung-Whan, Koh, Jae-Young, Cho, Dong-Hyung, Jo, Dong-Gyu
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Society for Neuroscience 2017
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Research Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6596467/
https://ncbi.nlm.nih.gov/pubmed/28432138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2385-16.2017
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