Inhibition of Drp1 Ameliorates Synaptic Depression, Aβ Deposition, and Cognitive Impairment in an Alzheimer's Disease Model

Excessive mitochondrial fission is a prominent early event and contributes to mitochondrial dysfunction, synaptic failure, and neuronal cell death in the progression of Alzheimer's disease (AD). However, it remains to be determined whether inhibition of excessive mitochondrial fission is benefi...

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Bibliografiska uppgifter
I publikationen:J Neurosci
Huvudupphovsmän: Baek, Seung Hyun, Park, So Jung, Jeong, Jae In, Kim, Sung Hyun, Han, Jihoon, Kyung, Jae Won, Baik, Sang-Ha, Choi, Yuri, Choi, Bo Youn, Park, Jin Su, Bahn, Gahee, Shin, Ji Hyun, Jo, Doo Sin, Lee, Joo-Yong, Jang, Choon-Gon, Arumugam, Thiruma V., Kim, Jongpil, Han, Jeung-Whan, Koh, Jae-Young, Cho, Dong-Hyung, Jo, Dong-Gyu
Materialtyp: Artigo
Språk:Inglês
Publicerad: Society for Neuroscience 2017
Ämnen:
Research Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6596467/
https://ncbi.nlm.nih.gov/pubmed/28432138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2385-16.2017
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