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The intracellular signalosome of PD-L1 in cancer cells
Programmed cell death-1 ligand-1 (PD-L1) overexpression in cancer cells accelerates tumor progression. PD-L1 possesses two main pro-oncogenic functions. First, PD-L1 is a strong immunosuppressive molecule that inactivates tumor-specific T cells by binding to the inhibitory receptor PD-1. Second, PD-...
Guardat en:
| Publicat a: | Signal Transduct Target Ther |
|---|---|
| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group UK
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6160488/ https://ncbi.nlm.nih.gov/pubmed/30275987 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41392-018-0022-9 |
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