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PD1 signal transduction pathways in T cells

The use of immune checkpoint inhibitors for the treatment of cancer is revolutionizing oncology. Amongst these therapeutic agents, antibodies that block PD-L1/PD1 interactions between cancer cells and T cells are demonstrating high efficacies and low toxicities. Despite all the recent advances, very...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Arasanz, Hugo, Gato-Cañas, Maria, Zuazo, Miren, Ibañez-Vea, Maria, Breckpot, Karine, Kochan, Grazyna, Escors, David
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5584302/
https://ncbi.nlm.nih.gov/pubmed/28881701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17232
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