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Systemic CD4 Immunity as a Key Contributor to PD-L1/PD-1 Blockade Immunotherapy Efficacy

PD-L1/PD-1 blockade immunotherapy has significantly improved treatment outcome for several cancer types compared to conventional cytotoxic therapies. However, the specific molecular and cellular mechanisms behind its efficacy are currently unclear. There is increasing evidence in murine models and i...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Zuazo, Miren, Arasanz, Hugo, Bocanegra, Ana, Fernandez, Gonzalo, Chocarro, Luisa, Vera, Ruth, Kochan, Grazyna, Escors, David
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7734243/
https://ncbi.nlm.nih.gov/pubmed/33329566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.586907
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