Systemic CD4 Immunity as a Key Contributor to PD-L1/PD-1 Blockade Immunotherapy Efficacy

PD-L1/PD-1 blockade immunotherapy has significantly improved treatment outcome for several cancer types compared to conventional cytotoxic therapies. However, the specific molecular and cellular mechanisms behind its efficacy are currently unclear. There is increasing evidence in murine models and i...

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Vydáno v:Front Immunol
Hlavní autoři: Zuazo, Miren, Arasanz, Hugo, Bocanegra, Ana, Fernandez, Gonzalo, Chocarro, Luisa, Vera, Ruth, Kochan, Grazyna, Escors, David
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7734243/
https://ncbi.nlm.nih.gov/pubmed/33329566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.586907
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