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Analysis of the association of EPHB6, EFNB1 and EFNB3 variants with hypertension risks in males with hypogonadism

Several members of the EPH kinase family and their ligands are involved in blood pressure regulation, and such regulation is often sex- or sex hormone-dependent, based on animal and human genetic studies. EPHB6 gene knockout (KO) in mice leads to hypertension in castrated males but not in un-manipul...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Wu, Tao, Zhang, Bi-Qi, Raelson, John, Yao, Yu-Mei, Wu, Huan-Dong, Xu, Zao-Xian, Marois-blanchet, Francois-christophe, Tahir, Muhammad Ramzan, Wang, Yujia, Bradley, W. Edward, Luo, Hongyu, Wu, Jiangping, Sheng, Jian-Zhong, Hu, Shen-Jiang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6160468/
https://ncbi.nlm.nih.gov/pubmed/30262919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-32836-x
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