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Analysis of the association of EPHB6, EFNB1 and EFNB3 variants with hypertension risks in males with hypogonadism

Several members of the EPH kinase family and their ligands are involved in blood pressure regulation, and such regulation is often sex- or sex hormone-dependent, based on animal and human genetic studies. EPHB6 gene knockout (KO) in mice leads to hypertension in castrated males but not in un-manipul...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Wu, Tao, Zhang, Bi-Qi, Raelson, John, Yao, Yu-Mei, Wu, Huan-Dong, Xu, Zao-Xian, Marois-blanchet, Francois-christophe, Tahir, Muhammad Ramzan, Wang, Yujia, Bradley, W. Edward, Luo, Hongyu, Wu, Jiangping, Sheng, Jian-Zhong, Hu, Shen-Jiang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6160468/
https://ncbi.nlm.nih.gov/pubmed/30262919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-32836-x
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