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Nuclear lamina dysfunction triggers a germline stem cell checkpoint

LEM domain (LEM-D) proteins are conserved components of the nuclear lamina (NL) that contribute to stem cell maintenance through poorly understood mechanisms. The Drosophila emerin homolog Otefin (Ote) is required for maintenance of germline stem cells (GSCs) and gametogenesis. Here, we show that ot...

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Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Barton, Lacy J., Duan, Tingting, Ke, Wenfan, Luttinger, Amy, Lovander, Kaylee E., Soshnev, Alexey A., Geyer, Pamela K.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6160405/
https://ncbi.nlm.nih.gov/pubmed/30262885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06277-z
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