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Nuclear lamina dysfunction triggers a germline stem cell checkpoint

LEM domain (LEM-D) proteins are conserved components of the nuclear lamina (NL) that contribute to stem cell maintenance through poorly understood mechanisms. The Drosophila emerin homolog Otefin (Ote) is required for maintenance of germline stem cells (GSCs) and gametogenesis. Here, we show that ot...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Barton, Lacy J., Duan, Tingting, Ke, Wenfan, Luttinger, Amy, Lovander, Kaylee E., Soshnev, Alexey A., Geyer, Pamela K.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6160405/
https://ncbi.nlm.nih.gov/pubmed/30262885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06277-z
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