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The Drosophila nuclear lamina protein Otefin is required for germline stem cell survival

LEM domain (LEM-D) proteins are components of an extensive protein network that assembles beneath the inner nuclear envelope. Defects in LEM-D proteins cause tissue-restricted human diseases associated with altered stem cell homeostasis. Otefin (Ote) is a Drosophila LEM-D protein that is intrinsical...

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Autori principali: Barton, Lacy J., Pinto, Belinda S., Wallrath, Lori L., Geyer, Pamela K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3710436/
https://ncbi.nlm.nih.gov/pubmed/23806619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2013.05.023
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