Selective insulin resistance with differential expressions of IRS-1 and IRS-2 in human NAFLD livers

BACKGROUND/OBJECTIVE: Insulin signals, via the regulation of key enzyme expression, both suppress gluconeogenesis and enhance lipid synthesis in the liver. Animal studies have revealed insulin signaling favoring gluconeogenesis suppression to be selectively impaired in steatotic livers. However, whe...

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Dades bibliogràfiques
Publicat a:Int J Obes (Lond)
Autors principals: Honma, Midori, Sawada, Shojiro, Ueno, Yoshiyuki, Murakami, Keigo, Yamada, Tetsuya, Gao, Junhong, Kodama, Shinjiro, Izumi, Tomohito, Takahashi, Kei, Tsukita, Sohei, Uno, Kenji, Imai, Junta, Kakazu, Eiji, Kondo, Yasuteru, Mizuno, Kei, Kawagishi, Naoki, Shimosegawa, Tooru, Katagiri, Hideki
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6160396/
https://ncbi.nlm.nih.gov/pubmed/29717275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41366-018-0062-9
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