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Dapagliflozin, a Sodium-Glucose Co-Transporter 2 Inhibitor, Acutely Reduces Energy Expenditure in BAT via Neural Signals in Mice

Selective sodium glucose cotransporter-2 inhibitor (SGLT2i) treatment promotes urinary glucose excretion, thereby reducing blood glucose as well as body weight. However, only limited body weight reductions are achieved with SGLT2i treatment. Hyperphagia is reportedly one of the causes of this limite...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Chiba, Yumiko, Yamada, Tetsuya, Tsukita, Sohei, Takahashi, Kei, Munakata, Yuichiro, Shirai, Yuta, Kodama, Shinjiro, Asai, Yoichiro, Sugisawa, Takashi, Uno, Kenji, Sawada, Shojiro, Imai, Junta, Nakamura, Kazuhiro, Katagiri, Hideki
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4786146/
https://ncbi.nlm.nih.gov/pubmed/26963613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0150756
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