Dapagliflozin, a Sodium-Glucose Co-Transporter 2 Inhibitor, Acutely Reduces Energy Expenditure in BAT via Neural Signals in Mice

Selective sodium glucose cotransporter-2 inhibitor (SGLT2i) treatment promotes urinary glucose excretion, thereby reducing blood glucose as well as body weight. However, only limited body weight reductions are achieved with SGLT2i treatment. Hyperphagia is reportedly one of the causes of this limite...

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Veröffentlicht in:PLoS One
Hauptverfasser: Chiba, Yumiko, Yamada, Tetsuya, Tsukita, Sohei, Takahashi, Kei, Munakata, Yuichiro, Shirai, Yuta, Kodama, Shinjiro, Asai, Yoichiro, Sugisawa, Takashi, Uno, Kenji, Sawada, Shojiro, Imai, Junta, Nakamura, Kazuhiro, Katagiri, Hideki
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4786146/
https://ncbi.nlm.nih.gov/pubmed/26963613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0150756
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