Genome-wide interaction with the insulin secretion locus MTNR1B reveals CMIP as a novel type 2 diabetes susceptibility gene in African Americans

Although type 2 diabetes (T2D) results from metabolic defects in insulin secretion and insulin sensitivity, most of the genetic risk loci identified to date relates to insulin secretion. We reported that T2D loci influencing insulin sensitivity may be identified through interactions with insulin sec...

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Detalhes bibliográficos
Publicado no:Genet Epidemiol
Main Authors: Keaton, Jacob M., Gao, Chuan, Guan, Meijian, Hellwege, Jacklyn N., Palmer, Nicholette D., Pankow, James S., Fornage, Myriam, Wilson, James G., Correa, Adolfo, Rasmussen-Torvik, Laura J., Rotter, Jerome I., Chen, Yii-Der I., Taylor, Kent D., Rich, Stephen S., Wagenknecht, Lynne E., Freedman, Barry I., Ng, Maggie C. Y., Bowden, Donald W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6160319/
https://ncbi.nlm.nih.gov/pubmed/29691896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.22126
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