Genome-Wide Interaction with Insulin Secretion Loci Reveals Novel Loci for Type 2 Diabetes in African Americans

Type 2 diabetes (T2D) is the result of metabolic defects in insulin secretion and insulin sensitivity, yet most T2D loci identified to date influence insulin secretion. We hypothesized that T2D loci, particularly those affecting insulin sensitivity, can be identified through interaction with insulin...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Keaton, Jacob M., Hellwege, Jacklyn N., Ng, Maggie C. Y., Palmer, Nicholette D., Pankow, James S., Fornage, Myriam, Wilson, James G., Correa, Adolfo, Rasmussen-Torvik, Laura J., Rotter, Jerome I., Chen, Yii-Der I., Taylor, Kent D., Rich, Stephen S., Wagenknecht, Lynne E., Freedman, Barry I., Bowden, Donald W.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4957757/
https://ncbi.nlm.nih.gov/pubmed/27448167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0159977
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