Genome-wide interaction with the insulin secretion locus MTNR1B reveals CMIP as a novel type 2 diabetes susceptibility gene in African Americans

Although type 2 diabetes (T2D) results from metabolic defects in insulin secretion and insulin sensitivity, most of the genetic risk loci identified to date relates to insulin secretion. We reported that T2D loci influencing insulin sensitivity may be identified through interactions with insulin sec...

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Vydáno v:Genet Epidemiol
Hlavní autoři: Keaton, Jacob M., Gao, Chuan, Guan, Meijian, Hellwege, Jacklyn N., Palmer, Nicholette D., Pankow, James S., Fornage, Myriam, Wilson, James G., Correa, Adolfo, Rasmussen-Torvik, Laura J., Rotter, Jerome I., Chen, Yii-Der I., Taylor, Kent D., Rich, Stephen S., Wagenknecht, Lynne E., Freedman, Barry I., Ng, Maggie C. Y., Bowden, Donald W.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6160319/
https://ncbi.nlm.nih.gov/pubmed/29691896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.22126
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