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Novel histone deacetylase inhibitors and embryo aggregation enhance cloned embryo development and ES cell derivation in pigs

The histone deacetylase inhibitor (HDACi) has been investigated for treating cancers and many other diseases as well as enhancing the reprogramming efficiency in cloned embryos for decades. In the present study, we investigated the effects of two novel HDAC inhibitors, i.e., HDACi-14 and -79, at the...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Siriboon, Chawalit, Li, Tzai-Shiuan, Yu, Chao-Wu, Chern, Ji-Wang, Ju, Jyh-Cherng
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6160101/
https://ncbi.nlm.nih.gov/pubmed/30261020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0204588
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