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Novel histone deacetylase inhibitors and embryo aggregation enhance cloned embryo development and ES cell derivation in pigs

The histone deacetylase inhibitor (HDACi) has been investigated for treating cancers and many other diseases as well as enhancing the reprogramming efficiency in cloned embryos for decades. In the present study, we investigated the effects of two novel HDAC inhibitors, i.e., HDACi-14 and -79, at the...

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Vydáno v:PLoS One
Hlavní autoři: Siriboon, Chawalit, Li, Tzai-Shiuan, Yu, Chao-Wu, Chern, Ji-Wang, Ju, Jyh-Cherng
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6160101/
https://ncbi.nlm.nih.gov/pubmed/30261020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0204588
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