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Alterations of functional circuitry in aging brain and the impact of mutated APP expression

Alzheimer's disease (AD) is a disease of aging that results in cognitive impairment, dementia and death. Pathognomonic features of AD are amyloid plaques composed of proteolytic fragments of the amyloid precursor protein (APP) and neurofibrillary tangles composed of hyperphosphorylated tau prot...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Neurobiol Aging
Päätekijät: Bearer, Elaine L., Manifold-Wheeler, Brett C., Medina, Christopher S., Gonzales, Aaron, Cháves, Frances, Jacobs, Russell E.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6159914/
https://ncbi.nlm.nih.gov/pubmed/30055413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2018.06.018
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