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Alterations of functional circuitry in aging brain and the impact of mutated APP expression

Alzheimer's disease (AD) is a disease of aging that results in cognitive impairment, dementia and death. Pathognomonic features of AD are amyloid plaques composed of proteolytic fragments of the amyloid precursor protein (APP) and neurofibrillary tangles composed of hyperphosphorylated tau prot...

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Dades bibliogràfiques
Publicat a:Neurobiol Aging
Autors principals: Bearer, Elaine L., Manifold-Wheeler, Brett C., Medina, Christopher S., Gonzales, Aaron, Cháves, Frances, Jacobs, Russell E.
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6159914/
https://ncbi.nlm.nih.gov/pubmed/30055413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2018.06.018
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