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Structural Studies of a Trinucleotide Repeat Sequence Using 2-Aminopurine

The secondary structure of repeated trinucleotide sequences result in the development of several neurodegenerative diseases, and these studies consider the (CAG)(8) sequence that forms a stem-loop hairpin. The structural and thermodynamic properties of this hairpin are assessed using 2-aminopurine s...

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Bibliografiske detaljer
Udgivet i:Biochemistry
Main Authors: Degtyareva, Natalya N., Reddish, Michael J., Sengupta, Bidisha, Petty, Jeffrey T.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6158780/
https://ncbi.nlm.nih.gov/pubmed/19170594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi802225y
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