Complement C3 Plays a Key Role in Inducing Humoral and Cellular Immune Responses to Influenza Virus Strain-Specific Hemagglutinin-Based or Cross-Protective M2 Extracellular Domain-Based Vaccination

The complement pathway is involved in eliminating antigen immune complexes. However, the role of the C3 complement system remains largely unknown in influenza virus M2 extracellular (M2e) domain or hemagglutinin (HA) vaccine-mediated protection after vaccination. Using a C3 knockout (C3 KO) mouse mo...

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Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: Kim, Yu-Jin, Kim, Ki-Hye, Ko, Eun-Ju, Kim, Min-Chul, Lee, Yu-Na, Jung, Yu-Jin, Lee, Young-Tae, Kwon, Young-Man, Song, Jae-Min, Kang, Sang-Moo
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2018
Sujets:
Vaccines and Antiviral Agents
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6158440/
https://ncbi.nlm.nih.gov/pubmed/30068650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00969-18
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